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hydroxy urea (d4)

Hydroxyurea

CAS: 127-07-1

Molecular Formula: CH4N2O2

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hydroxy urea (d4) - Names and Identifiers

Name Hydroxyurea
Synonyms HU
Hidrix
Hydura
Hydrea
Litaler
Hydurea
Oxyurea
sq 1089
Hydreia
Litalir
wr 83799
sk 22591
Hydroxyurea
Biosupressin
Hydroxy urea
Hydroxylurea
Onco-carbide
N-Hydroxyurea
N-HYDROXYUREA
1-hydroxyurea
Carbamoyl oxime
Hydroxycarbamine
Hidroxicarbamida
Hydroxycarbamide
hydrixycarbamide
hydroxy urea (d4)
Carbamyl hydroxamate
Carbamohydroximic acid
Carbamohydroxamic acid
N-Carbamoylhydroxylamine
N-(aminocarbonyl)hydroxylamine
CAS 127-07-1
EINECS 204-821-7
InChI InChI=1/CH4N2O2/c2-1(4)3-5/h3H2,(H2,2,4)

hydroxy urea (d4) - Physico-chemical Properties

Molecular FormulaCH4N2O2
Molar Mass76.05
Density1.457±0.06 g/cm3(Predicted)
Melting Point135-140°C
Boling Point136.04°C (rough estimate)
Water Solubilitysoluble
Solubility Soluble in water and hot ethanol, slightly soluble in cold ethanol, insoluble in ether; benzene.
AppearanceWhite powder
Colorwhite
Merck14,4848
BRN1741548
pKa10.56±0.23(Predicted)
Storage Condition2-8°C
StabilityStable for 2 years as supplied from date of purchase. Solutions in water may be stored at -20°C for up to 3 months.
Refractive Index1.4840 (estimate)
MDLMFCD00007943
Physical and Chemical PropertiesMelting point 142-146°C
water-soluble solution
UseAnti-metabolic anticancer drugs, mainly acting on the G1 and S phase of proliferating cells, have a delaying effect on the G1/S interface, and are cell-specific drugs

hydroxy urea (d4) - Risk and Safety

Risk CodesR46 - May cause heritable genetic damage
R63 - Possible risk of harm to the unborn child
R61 - May cause harm to the unborn child
R40 - Limited evidence of a carcinogenic effect
Safety DescriptionS53 - Avoid exposure - obtain special instructions before use.
S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36 - Wear suitable protective clothing.
S22 - Do not breathe dust.
UN IDs2811
WGK Germany3
RTECSYT4900000
HS Code29242100
Hazard NoteToxic
Hazard Class6.1
Packing GroupIII

hydroxy urea (d4) - Reference

Reference
Show more
1. Yang Tao. Establishment and Evaluation of Rat CKD Model of Kidney Yang Deficiency Induced by Adriamycin Combined with Hydroxyurea and Study on Intervention Mechanism of Zhenwu Decoction [D]. Beijing University of Traditional Chinese Medicine, 2020.

hydroxy urea (d4) - Introduction

This product is a nucleoside diphosphate reductase inhibitor, which can prevent the reduction of nucleotides to deoxynucleotides, interfere with purine and pyrimidine base biosynthesis, selectively hinder DNA synthesis, and have no blocking effect on RNA and protein synthesis. Cycle-specific drugs, S-phase cells are sensitive.
Last Update:2022-10-16 17:13:02
hydroxy urea (d4)
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 127-07-1
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Shanghai Yuanye Bio-Technology Co., Ltd.
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CAS: 127-07-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Hydroxy urea Visit Supplier Webpage Request for quotation
CAS: 127-07-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
MedChemExpress (MCE)
Featured ProductsMultiple SpecificationsSpot supply
Product Name: Hydroxycarbamide Visit Supplier Webpage Request for quotation
CAS: 127-07-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Guangzhou Yuanda New Material Co.,Ltd
Spot supply
Product Name: Hydroxyurea;Hydroxycarbamide;N-HYDROXYUREA Request for quotation
CAS: 127-07-1
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Hydroxyurea Request for quotation
CAS: 127-07-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Hydroxyurea Visit Supplier Webpage Request for quotation
CAS: 127-07-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Hydroxyurea Visit Supplier Webpage Request for quotation
CAS: 127-07-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Hydroxyurea Visit Supplier Webpage Request for quotation
CAS: 127-07-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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hydroxy urea (d4)
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